FA Analyses: Lipid Profiles and Blood Pressure in Stroke-Prone Hypertensive Rats

Experimental data from a study on the effects of a cholesterol-enriched diet on stroke-prone spontaneously hypertensive rats (SHRSP). The dataset includes measurements of sterol content, fatty acid composition, prostaglandin E2 levels, systolic blood pressure, and renal histopathology from a 12-week feeding trial. The data was authored by Yutaro Nishikata and last updated on 2026-05-21.

Use Cases

• Analyzing the relationship between dietary cholesterol and systolic blood pressure based on pre- and post-feeding measurements.
• Investigating changes in organ lipid profiles, including phytosterol content and arachidonic acid ratios, based on the described analyses.
• Correlating lipidomic changes with renal pathological features based on the histological analysis mentioned in the description.
• Studying the suppression of the AA-PGE2 axis in the context of dietary interventions based on the reported hepatic and kidney PGE2 level trends.

Strengths

• Data is associated with a specific, detailed experimental protocol involving three distinct diet groups over a 12-week period.
• Includes multiple biological measurements: systolic blood pressure, sterol content, fatty acid composition, PGE2 levels, and histopathology.
• Dataset is openly available under a CC-BY-4.0 license, facilitating reuse and sharing.

Limitations

• Dataset is very small at 31.5 KB, indicating a limited scope and likely a small sample size.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for statistical modeling.

Provenance

Source

figshare, authored by Yutaro Nishikata.

Collection Method

Data was generated from a controlled laboratory experiment on SHRSP/Izm rats.

Freshness

Last updated 2026-05-21 17:26:45; freshness should be verified.