Data of sterol analyses from a study on stroke-prone spontaneously hypertensive rats (SHRSP). The dataset, authored by Yutaro Nishikata and last updated in May 2026, contains measurements of sterol content, fatty acid composition, prostaglandin E2 levels, and histopathology from rats fed cholesterol-enriched diets. The file is 14.9 KB in size and is available in XLSX format.
Use Cases
- Analyze the relationship between dietary cholesterol and systolic blood pressure based on the reported 9–10% reduction.
- Investigate changes in organ lipid profiles, including phytosterol content and arachidonic acid ratios, as described in the study.
- Examine correlations between lipid alterations and renal pathology attenuation mentioned in the histological analysis.
- Study the suppression of the AA-PGE2 axis in serum, kidney, and liver tissues as outlined in the mechanistic framework.
Strengths
- Dataset is focused on a specific, well-defined animal model (SHRSP/Izm rats) and experimental design with three diet groups.
- Includes multiple related biological measurements: sterol content, fatty acid composition, PGE2 levels, and histopathology, allowing for integrated analysis.
- Published under a permissive CC-BY-4.0 license, facilitating reuse and sharing.
Limitations
- Row count is unknown, which may limit suitability assessment for statistical modeling.
- Column-level documentation is absent; field semantics must be inferred after download.
- The dataset is very small (14.9 KB), indicating a limited scope of observations.
Provenance
- Source
- Yutaro Nishikata via figshare
- Collection Method
- Experimental data collected from a controlled animal feeding study.
- Freshness
- Last updated 2026-05-21 17:26:46; freshness should be verified.