Zebrafish Yap1 Mutant Phenotype Data for Scoliosis Research

Victoria C. Williams-Ward's dataset on figshare contains experimental data on zebrafish with Yap1 gene mutations, investigating their role in vertebral development and kyphoscoliosis. The dataset is 146.7 KB in size and was last updated on May 28, 2026. It is shared under a CC-BY-4.0 license.

Use Cases

• Analyze the correlation between Yap1 mutation and vertebral dysmorphology based on the described phenotype.
• Study the temperature-sensitive rescue of cardiac oedema in Yap1 mutants based on the experimental conditions mentioned.
• Investigate the temporal progression of kyphoscoliosis from early larval stages based on the described developmental timeline.
• Examine the relationship between early motility defects and later skeletal abnormalities based on the described feedback mechanism.

Strengths

• Dataset is focused on a specific genetic model (Yap1 mutants) with a fully penetrant vertebral phenotype.
• Includes temporal data points from 1-2 days post-fertilisation to adulthood, as described.
• Licensed under CC-BY-4.0, permitting broad reuse with attribution.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The 146.7 KB file size suggests a limited scope of data.

Provenance

Source

Victoria C. Williams-Ward

Collection Method

Likely contains experimental data from zebrafish studies of Yap1 and Wwtr1/Taz gene mutations.

Freshness

Last updated 2026-05-28 17:39:55; freshness should be verified.