Granulosa Cell Cuproptosis and tRF-Gly-M3 Expression Data

A figshare dataset by Linyuan Shen, last updated on April 30, 2026, investigates the molecular mechanisms of copper-induced cell death (cuproptosis) in ovarian granulosa cells. The 783.8 KB XLSX file contains data linking tRNA-derived fragments, particularly tRF-Gly-M3, to mitochondrial dysfunction and impaired oocyte development. The dataset is licensed under CC-BY-4.0 for open use.

Use Cases

• Modeling the relationship between copper accumulation and mitochondrial TCA cycle disruption based on described metabolic measurements.
• Analyzing the role of tRNA-derived fragments (tRFs) in cellular copper homeostasis based on the identified correlation.
• Investigating intercellular communication via exosomes by studying tRF-Gly-M3 transfer from granulosa cells to oocytes.
• Studying the functional impact of tRF-Gly-M3 on oocyte maturation and parthenogenesis based on the described silencing of GLS mRNA.

Strengths

• Dataset is openly licensed under CC-BY-4.0.
• File size is 783.8 KB, indicating a focused and likely manageable dataset.
• Last update timestamp is precisely recorded as 2026-04-30 17:40:19.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

Linyuan Shen via figshare.

Collection Method

Likely contains experimental data from a study on granulosa cell cuproptosis.

Freshness

Last updated 2026-04-30 17:40:19; freshness should be verified.