Cdc42 Protein Expression Levels and Cell Fusion in Schizosaccharomyces pombe

A 100 KB Excel dataset from figshare, uploaded by Sajjita Saha in March 2026, likely contains experimental data on the Cdc42 GTPase protein. The description indicates the dataset includes measurements from an allelic series driving Cdc42 expression over a 5-fold range, comparing its role in mitotic polarized growth versus mating in fission yeast.

Use Cases

• Analyze the relationship between Cdc42 protein levels and mitotic polarized growth based on the allelic series described.
• Model the switch-like response of mating versus linear growth response based on Cdc42 expression levels.
• Investigate cell fusion defects and actin focus formation based on the cdc42-mCherrySW allele data.
• Compare protein instability and functional requirements between mating and growth phases based on Cdc42-mCherrySW observations.

Strengths

• Data is structured in an Excel (XLSX) format, facilitating direct analysis.
• Includes a specific allelic series with Cdc42 expression driven over a 5-fold range.
• Explicitly compares two distinct biological processes: mitotic polarized growth and mating.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare

Freshness

Last updated 2026-03-19 17:29:33; freshness should be verified.