<p>DEG list associated with cancer.</p>

A list of differentially expressed genes (DEGs) associated with hepatocellular carcinoma prognosis, derived from a study of 345 primary tumor specimens. The dataset was generated by author Norihiko Suzaki and published on figshare in April 2026. It likely contains gene identifiers and expression or association metrics from RNA sequencing and functional analyses of the histone methyltransferase SETD8/KMT5A.

Use Cases

• Identify potential prognostic biomarkers for hepatocellular carcinoma based on gene expression patterns described in the study.
• Analyze gene ontology terms related to cancer progression, such as cell adhesion and MAPK signaling, referenced in the description.
• Validate or compare gene lists from other studies focusing on SETD8/KMT5A or epigenetic regulation in cancer.
• Support hypothesis generation for in vitro or in vivo functional studies of cancer-related genes.

Strengths

• Data is derived from a study of 345 primary hepatocellular carcinoma resection specimens, providing a clinical foundation.
• Analysis includes both in vitro assays (proliferation, cell cycle, invasion) and in vivo xenograft experiments, suggesting multi-modal validation.
• Published under a permissive CC-BY-4.0 license, allowing for reuse and redistribution.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is very small (5.5 KB), indicating a limited scope, likely a focused gene list rather than raw sequencing data.

Provenance

Source

figshare

Collection Method

Generated from immunohistochemical staining of 345 specimens, RNA sequencing, and gene ontology analysis of hepatocellular carcinoma cell lines.

Time Range

Study period not specified; dataset reflects analysis from the associated research.

Freshness

Last updated 2026-04-13 17:32:58; freshness should be verified.

Geography

Geographic origin of specimens not specified.