DEGs from ΔeecP vs OG1RF: Bacterial Gene Expression in Immune Response

A 10.0 KB Excel file contains differentially expressed genes (DEGs) from a comparison of Enterococcus faecalis strains ΔeecP and OG1RF at time point T0. The dataset, authored by Adriana G. Morales Rivera and last updated on 2026-05-21, was generated to study the role of the extracellular nucleotidase EecP in bacterial immune evasion and pathogenesis.

Use Cases

• Identify bacterial genes differentially regulated by the loss of the EecP enzyme based on the described strain comparison.
• Investigate links between extracellular c-di-AMP levels and host immune gene signatures based on the described NanoString analysis.
• Correlate genetic expression changes with phenotypic outcomes like phagocyte susceptibility mentioned in the description.

Strengths

• Dataset is openly licensed under CC-BY-4.0.
• Specific biological context is provided, detailing the role of EecP in c-di-AMP degradation and immune evasion.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The 10.0 KB size suggests a limited scope, likely containing summary statistics rather than raw sequencing data.

Provenance

Source

Adriana G. Morales Rivera, via figshare.

Collection Method

Likely derived from gene expression analysis (e.g., RNA-seq) comparing bacterial strains.

Freshness

Last updated 2026-05-21 07:38:13; freshness should be verified.