DEGs from ΔeecP vs OG1RF: Differentially Expressed Genes in Enterococcus faecalis

Differentially expressed genes (DEGs) from a comparison of an Enterococcus faecalis ΔeecP mutant strain and the parent strain OG1RF at time point T2. The dataset was authored by Adriana G. Morales Rivera and last updated on 2026-05-21. It is a 12.5 KB XLSX file shared under a CC-BY-4.0 license on figshare.

Use Cases

• Identify bacterial genes differentially regulated by the loss of the EecP enzyme based on the described mutant comparison.
• Investigate links between extracellular c-di-AMP levels and host immune gene signatures based on the described NanoString analysis of infected macrophages.
• Correlate genetic changes with phenotypic outcomes like susceptibility to phagocytic killing mentioned in the description.
• Explore potential targets for modulating infection severity in disseminated models based on the described murine infection experiments.

Strengths

• Dataset is focused on a specific, well-defined genetic comparison (ΔeecP vs. OG1RF at T2).
• Data is shared under a permissive CC-BY-4.0 license, allowing for broad reuse.
• File size is 12.5 KB, indicating a compact and likely focused dataset.

Limitations

• Row count is unknown, which may limit suitability assessment for large-scale analyses.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality and normalization methods require manual inspection.

Provenance

Source

Adriana G. Morales Rivera, via figshare.

Collection Method

Likely derived from transcriptomic analysis (e.g., RNA-seq or microarray) comparing bacterial strains, as inferred from the description of DEGs and NanoString analysis.

Freshness

Last updated 2026-05-21 07:38:14; freshness should be verified.