DEGs from RNA Sequencing of SETD8 Knockdown in SNU475 Cells

374.3 KB of differentially expressed genes identified via RNA sequencing. Norihiko Suzaki published this dataset under a CC-BY-4.0 license on figshare, with a last update in April 2026. The data compares gene expression between siSETD8-treated and control-treated SNU475 hepatocellular carcinoma cells.

Use Cases

• Identify potential therapeutic targets based on genes differentially expressed after SETD8 knockdown.
• Validate RNA-seq analysis pipelines using a focused dataset of DEGs.
• Investigate the role of histone methyltransferase SETD8 in hepatocellular carcinoma cell lines.

Strengths

• Data is openly licensed under CC-BY-4.0.
• File size of 374.3 KB indicates a focused, manageable dataset for targeted analysis.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare, author Norihiko Suzaki.

Collection Method

RNA sequencing analysis comparing treated and control cell samples.

Time Range

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Freshness

Last updated 2026-04-13 17:32:36; freshness should be verified.

Geography

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