Demographic and Thrombin Generation Data for 102 High-Risk Pregnant Women

A prospective cohort study of 102 high-risk pregnant women, evaluating longitudinal endogenous thrombin potential in relation to preeclampsia or gestational diabetes mellitus. The dataset includes thrombin generation measurements from gestational weeks 8–15, with follow-ups every 2–12 weeks, and was published by Harald Haidl on figshare in 2026. Eleven women developed preeclampsia, and 19 developed gestational diabetes mellitus.

Use Cases

• Analyzing the relationship between early-pregnancy endogenous thrombin potential and subsequent development of preeclampsia based on thrombin generation values.
• Investigating the moderating effect of acetylsalicylic acid therapy on thrombin potential progression in gestational diabetes mellitus patients.
• Building predictive models for pregnancy complications using longitudinal biomarker data collected from the first trimester.
• Studying the longitudinal progression of hemostatic imbalance in high-risk pregnancies based on repeated measurements.

Strengths

• Includes longitudinal data with samples collected from gestational weeks 8–15 and follow-ups every 2–12 weeks.
• Provides specific thrombin potential values for patient subgroups: 2220 ± 357 nM*min for preeclampsia, 2298 ± 377 nM*min for gestational diabetes, and 1995 ± 337 nM*min for the rest of the cohort.
• Dataset is small (5.5 KB) and likely focused, facilitating quick inspection and analysis.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset's 5.5 KB size indicates a very limited scope, likely containing summary or aggregated data rather than raw individual-level records.

Provenance

Source

Harald Haidl via figshare

Collection Method

Prospective cohort study using Calibrated Automated Thrombography on blood samples.

Time Range

Data collection spanned from gestational weeks 8–15 with follow-ups.

Freshness

Last updated 2026-04-21 17:24:22; freshness should be verified.

Geography

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