Descriptive Blast Analysis of citk-1 in C. elegans Neurons

18.5 KB of descriptive results from a suppressor screen investigating microtubule regulation in C. elegans PLM neurons. The data, authored by Sunanda Sharma and last updated in April 2026, focuses on the role of the cytokinesis-associated protein CITK-1 and its interaction with ASPM-1. The findings suggest non-mitotic roles for these proteins in modulating microtubule stability and polarity in differentiated neurons.

Use Cases

• Analyze genetic suppressor screen results based on the described isolation of tubulin and citk-1 variants.
• Study microtubule stability and polarity in neurons based on the described role of CITK-1/2 in PLM neuron processes.
• Investigate genetic pathways involving cytokinesis-associated proteins based on the described interaction between CITK-1/2 and ASPM-1.
• Examine morphological defects in neurons based on the described neurite growth and synaptic branch phenotypes.

Strengths

• Data is openly licensed under CC-BY-4.0.
• File size is 18.5 KB, indicating a focused and potentially quick-to-analyze dataset.
• The description provides a detailed biological context for the suppressor screen and its findings.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is small (18.5 KB), indicating limited scope.

Provenance

Source

figshare, author Sunanda Sharma.

Collection Method

Likely generated from a genetic suppressor screen in C. elegans, as described.

Freshness

Last updated 2026-04-15 18:01:09; freshness should be verified.