Design Files for ThermiQuant AquaStream Microfluidic Diagnostic Device

ThermiQuant AquaStream is a portable benchtop device costing USD 327 that supports colorimetric LAMP reactions in both tubes and microfluidic paper-based analytical devices (µPADs). The system enables real-time reaction tracking every 30 seconds, precise isothermal control (±0.5 °C), and medium-throughput of 24 tubes or 42 µPADs. Bibek Raut published these design files on figshare under a CC-BY-4.0 license in May 2026.

Use Cases

• Replicate the ThermiQuant AquaStream hardware based on the provided design files.
• Develop or optimize colorimetric LAMP assays for pathogens using the described tube and µPAD formats.
• Compare assay performance between liquid-phase (tube) and paper-based (µPAD) formats within a common workflow.
• Conduct proof-of-concept research for molecular diagnostics in field-deployable settings.

Strengths

• Device cost is specified as USD 327, enabling low-cost replication.
• Performance metrics are provided, including a limit of detection (LOD95) of 110 copies per reaction in tubes and 39 copies in µPADs.
• The system offers precise temperature control (±0.5 °C) and real-time monitoring every 30 seconds.
• Design files are openly shared under a permissive CC-BY-4.0 license.

Limitations

• The dataset is small (2.2 MB), suggesting it contains design files rather than large experimental data.
• Row count and column-level documentation are absent; data structure must be inferred after download.
• The description focuses on the device and a proof-of-concept test; the breadth of included experimental data is unclear.

Provenance

Source

figshare

Collection Method

Design files for a custom-built research device.

Freshness

Last updated 2026-05-15 17:51:46.