Details of Genomic Binding Analysis for 11 Regulatory Proteins

Maik Mendler's dataset provides genomic binding analysis for 11 regulatory proteins, published on figshare in April 2026. The 15.7 MB XLSX file contains two tabs: one with occupancy data for 300 bp wide genomic bins and another with occupancy data for genes. The data includes assigned regulatory complexes and combinations of TRB paralogs.

Use Cases

• Mapping transcription factor occupancy across the genome based on the 300 bp bin-level data.
• Correlating regulatory protein binding with gene expression clusters using the gene-level RNAseq cluster data.
• Analyzing the composition and co-occurrence of regulatory complexes from the assigned complex data.
• Studying the functional roles of TRB paralog combinations in gene regulation.

Strengths

• Data is structured in two distinct, purpose-specific tabs (genomic bins and genes).
• Includes analysis for 11 distinct regulatory proteins.
• Released under a permissive CC-BY-4.0 license.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

Maik Mendler

Collection Method

Likely derived from genomic binding assays (e.g., ChIP-seq) and RNA sequencing.

Freshness

Last updated 2026-04-21 17:51:27; freshness should be verified.