Di-Gly MS Dataset: Ubiquitylated Peptides in Mtb-Infected Macrophages

The Di-Gly MS dataset contains over 46,000 ubiquitylated peptides identified via mass spectrometry from Mycobacterium tuberculosis (Mtb)-infected macrophages. It includes roughly 400 peptides with CBL-dependent ubiquitylation. The dataset was authored by Tina Truong and last updated on March 17, 2026.

Use Cases

• Identify potential CBL substrates based on CBL-dependent ubiquitylation patterns.
• Analyze ubiquitin-mediated signaling events in Mtb-infected macrophages.
• Perform genetic interaction analysis linking ubiquitin ligases to adapter proteins like FAF2.
• Investigate the regulation of antiviral versus antibacterial response genes in infected cells.

Strengths

• Contains over 46,000 identified ubiquitylated peptides.
• Includes roughly 400 peptides with specifically CBL-dependent ubiquitylation.
• Data is available in an XLSX file format, accessible for spreadsheet analysis.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

Tina Truong via figshare.

Collection Method

Mass spectrometry analysis of ubiquitylated peptides.

Time Range

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Freshness

Last updated 2026-03 17:36:41; freshness should be verified.

Geography

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