Dissociation Constants and MICs for Chemoreceptors PacH, PacI, and PacG

Dissociation constants derived from microcalorimetric binding studies to the ligand binding domains of chemoreceptors PacH, PacI and PacG and minimal inhibitory concentrations (MIC). The 5.5 KB dataset was authored by Roberta Genova and last updated on May 21, 2026. It is shared under a CC-BY-4.0 license on the figshare platform.

Use Cases

• Modeling protein-ligand binding affinity based on dissociation constants from microcalorimetry.
• Correlating ligand binding data with antimicrobial activity based on minimal inhibitory concentrations (MIC).
• Studying chemoreceptor function in bacterial signaling pathways based on data for PacH, PacI, and PacG.
• Benchmarking computational binding prediction models against experimental microcalorimetry data.

Strengths

• Data is derived from experimental microcalorimetric binding studies, a direct measurement technique.
• Includes both binding affinity (dissociation constants) and functional antimicrobial activity (MIC) data.
• Shared under a permissive CC-BY-4.0 license, allowing for wide reuse.

Limitations

• The dataset is very small at 5.5 KB, indicating limited scope.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for statistical analysis.

Provenance

Source

figshare

Collection Method

Microcalorimetric binding studies.

Freshness

Last updated 2026-05-21 07:39:48; freshness should be verified.