Transcriptomic data from a 72-hour fermentation experiment comparing a Streptomyces clavuligerus strain overexpressing the bldD regulator to a control. The dataset, created by Luisa F. Patiño and last updated in April 2026, likely contains gene expression changes related to antibiotic production and morphological development. It is provided as a 108.1 KB XLSX file.
Use Cases
- Identify genes differentially expressed under BldD overexpression based on the transcriptomic comparison.
- Analyze the repression of cephamycin C biosynthesis genes (e.g., lat, ccaR) mentioned in the description.
- Study the upregulation of terpene biosynthesis and phage tail-like particle (CIS) genes described in the experiment.
- Investigate the link between BldD, morphological differentiation (e.g., bldN, bldM, chaplins), and metabolic flux.
Strengths
- Data is focused on a specific 72-hour time point in a controlled fermentation experiment.
- The dataset is licensed under CC-BY-4.0, permitting open sharing and adaptation.
- The description provides specific biological context regarding regulated pathways and genes.
Limitations
- Column-level documentation is absent; field semantics must be inferred after download.
- Row count is unknown, which may limit suitability assessment.
- The dataset is small (108.1 KB), indicating a limited scope of observations.
Provenance
- Source
- figshare
- Collection Method
- Transcriptomic analysis of Streptomyces clavuligerus fermentation samples.
- Time Range
- Data from a 72-hour fermentation experiment.
- Freshness
- Last updated 2026-04 22 17:27:47; freshness should be verified.
- Geography
- null