Prion Infectivity Titers from Brain, Spleen, and Muscle Homogenates

End-point RT-QuIC titration data for cell lysate infected with prions from different tissue homogenates. Each value is a log SD50 per gram of tissue, computed by Spearman-Kärber analysis. The dataset was authored by Joseph P. DeFranco and last updated on June 4, 2026.

Use Cases

• Compare prion infectivity titers based on tissue source (brain, spleen, or muscle).
• Analyze the relationship between passage number and infectivity levels.
• Validate RT-QuIC assay results using Spearman-Kärber statistical analysis.

Strengths

• Data includes quantitative log SD50 values for infectivity.
• Results are derived from a standardized 0.3% (w/v) homogenate concentration.
• Dataset is openly available under a CC-BY-4.0 license.

Limitations

• The dataset is very small at 5.5 KB, indicating limited scope.
• Row count and column-level documentation are unknown.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare

Collection Method

End-point RT-QuIC titration analysis of infected cell lysate.

Freshness

Last updated 2026-06-04 17:41:28; freshness should be verified.