Parkinson's Disease Gene Enrichment in Brain Co-Expression Modules

Enrichment analysis results for Parkinson's disease-associated genes, differentially expressed genes, and SNPs across ten brain regions. The 7.2 MB XLSX file was authored by Jiafang Li and last updated on May 29, 2026. Data is shared under a CC-BY-4.0 license on the figshare platform.

Use Cases

• Identify brain-region-specific genetic associations for Parkinson's disease based on the enrichment of PD-associated genes.
• Prioritize candidate genes for functional studies based on their enrichment in specific co-expressed modules (SCMs).
• Investigate the convergence of genetic risk (SNPs) and gene expression changes (DGEs) in Parkinson's disease pathology.
• Compare molecular signatures of Parkinson's disease across the ten different brain regions mentioned in the description.

Strengths

• Data is focused on ten distinct brain regions, allowing for comparative analysis.
• The dataset includes multiple data types (genes, DGEs, SNPs) integrated into a single enrichment analysis.
• File size is 7.2 MB, indicating a manageable dataset for local analysis.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for certain statistical methods.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

figshare

Freshness

Last updated 2026-05-29 18:00:13; freshness should be verified.