Truncated RBP2 Variant Activity on Klebsiella Capsular Types

Agnieszka Latka published this 5.5 KB Excel dataset in 2026, detailing the enzymatic activity of wild-type and truncated variants of the RBP2 protein. It compares activity across constructed protein derivatives and their individual domains. Data shows presence or absence of activity on two specific Klebsiella pneumoniae strains.

Use Cases

• Correlate the presence or deletion of specific protein domains (e.g., CP, E, LIN, CBM, LEC) with the binary activity outcome on Kp358 (K21) and Kp968 (KL163) strains.
• Analyze the functional impact of amino acid delineation ranges for each truncated variant compared to the wild-type RBP2 sequence.
• Compare enzymatic activity patterns between full-length protein constructs and individual, isolated domain constructs.

Strengths

• Data is structured for direct comparison of activity across 10+ constructed protein variants.
• Clear binary (Blue/NO) activity annotation for two distinct bacterial capsular types provides a simple classification target.

Limitations

• The dataset is very small at 5.5 KB, limiting statistical analysis and machine learning applications.
• Activity data is limited to only two Klebsiella pneumoniae strains (Kp358 and Kp968), reducing generalizability.
• No quantitative activity measurements (e.g., kinetic rates) are provided, only a binary presence/absence.

Provenance

Source

Figshare, authored by Agnieszka Latka.

Collection Method

Experimental measurement of enzymatic activity for laboratory-constructed protein variants.

Freshness

Last updated in April 2026.