Evaluation Results of MoGSA: Cefotaxime Sodium Synthesis Optimization

Experimental results from optimizing the synthesis process of cefotaxime sodium (CTX) using the Box-Behnken response surface method. The dataset includes yield, impurity content, and green chemistry evaluation scores under varying conditions of temperature, eluent dosage, and salt-forming agent ratio. The data was authored by Wang Yizhang and last updated on 2026-05-14.

Use Cases

• Optimizing chemical reaction parameters based on yield and impurity data
• Evaluating environmental performance of a synthesis process based on green chemistry scores
• Characterizing product quality based on HPLC, XRD, and SEM analysis results

Strengths

• Specific optimal process conditions are provided: reaction temperature 14.8°C, eluent dosage 104.4 mL, and salt-forming agent ratio 1:1
• Quantitative results are reported: a yield of 93.66%, total impurity content of 3.93%, and a green chemistry evaluation score of 94.44

Limitations

• Row count is unknown, which may limit suitability assessment
• Column-level documentation is absent; field semantics must be inferred after download

Provenance

Source

figshare

Collection Method

Data likely originates from laboratory experiments using single-factor tests and Box-Behnken response surface methodology.

Freshness

Last updated 2026-05-14 17:29:31; freshness should be verified