Exact P Values for Hepatocellular Carcinoma Spatial Omics Analysis

A figshare dataset provides the exact statistical p-values corresponding to Figure 1g from a study on hepatocellular carcinoma (HCC). The underlying research integrated spatial transcriptomics and metabolomics from six tissue samples across four patients to investigate cellular mechanisms linked to microvascular invasion (MVI). The data was published by author Zhi-Hui Luo under a CC-BY-4.0 license and last updated in May 2026.

Use Cases

• Statistical validation of findings related to the STMN1+HMGN2+GPC3+ cell subtype based on the reported p-values.
• Re-analysis of the association between microvascular invasion status and gene expression patterns in hepatocellular carcinoma.
• Meta-analysis incorporating the reported p-values from the study's multiplex immunofluorescence staining validation in a cohort of 79 patients.
• Methodological reference for integrating spatial transcriptomics and metabolomics data in cancer research.

Strengths

• Provides precise statistical values (p-values) for a key figure from a peer-reviewed spatial omics study.
• Data is openly available under a permissive CC-BY-4.0 license.
• The associated research includes validation across multiple cohorts, including a TCGA-LIHC cohort (n=299) and an independent microarray dataset (n=62).

Limitations

• The dataset is very small (15.8 KB), containing only the p-values for a single figure, not the underlying raw or processed omics data.
• Row count and column definitions are unknown, requiring manual inspection after download to understand the data structure.
• The source study notes a limitation of a small sample size for the spatial omics data, which may affect the generalizability of the findings these p-values support.

Provenance

Source

figshare

Collection Method

Derived from statistical analysis performed in a research study integrating spatial transcriptomics and metabolomics.

Freshness

Last updated 2026-05-15 18:00:32.