Cellular Gene Expression in Lytic HH514-16 Cells

Examples of cellular genes showing preferential up-regulation in lytic HH514-16 cells compared to untreated or refractory cells. The data is derived from microarray analysis of sorted cell subpopulations treated with NaB for 24 hours, published in Hill et al. Derek Daigle uploaded this dataset to figshare in May 2026.

Use Cases

• Identify candidate genes involved in viral lytic reactivation based on differential expression.
• Validate microarray findings from the referenced publication (Hill et al.) using the provided gene list.
• Compare gene expression profiles between lytic and refractory cell states under NaB treatment.

Strengths

• Dataset is small (5.5 KB), facilitating quick download and inspection.
• Data is associated with a specific, peer-reviewed publication (Hill et al.), providing context.

Limitations

• The dataset is very small (5.5 KB), suggesting it contains only a limited subset of results, not the full microarray data.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

figshare

Collection Method

Microarray analysis (Affymetrix U133 Plus 2.0 arrays) of total RNA from sorted cell subpopulations.

Freshness

Last updated 2026-05-11 17:46:06; freshness should be verified.