Transcriptomic Data from Ex Vivo Whole-Blood Infection Model for Pertussis

An Excel file containing transcriptomic data from a study comparing neonatal and adult immune responses to Bordetella pertussis. The 725.8 KB dataset, authored by Soraya Matczak and last updated in April 2026, profiles an ex vivo whole-blood infection model. It likely contains gene expression data revealing a hyperinflammatory cytokine signature and B cell remodeling in cord blood.

Use Cases

• Compare pro-inflammatory immune responses between cord blood and adult blood based on the described cytokine signature.
• Analyze B cell remodeling and activation marker expression based on the described CD25+ B lymphocyte phenotype.
• Investigate innate immune cell activation skewing in neonatal blood based on the transcriptomic analysis mentioned.
• Model early systemic immune events in pertussis infection using the described ex vivo whole-blood infection data.

Strengths

• Data is from a specialized ex vivo whole-blood infection model, a noted advantage in the description.
• Dataset is openly available under a CC-BY-4.0 license.
• File is a manageable 725.8 KB XLSX, facilitating direct inspection.

Limitations

• Row count and column-level documentation are unknown, which may limit suitability assessment.
• The dataset's 725.8 KB size suggests a limited scope, potentially containing summary results rather than raw sequencing data.

Provenance

Source

figshare, author Soraya Matczak.

Collection Method

Multi-omic profiling of an ex vivo whole-blood infection model, as described.

Time Range

null

Freshness

Last updated 2026-04-22 17:38:56; freshness should be verified.

Geography

null