Experimental Data on Cadmium Toxicity in Freshwater Crab Gills

Freshwater crabs Sinopotamon henanense were exposed to four concentrations of cadmium (0, 14.5, 29, and 58 mg/L) for 4 days. The dataset, published by Jianxia Liu on figshare in April 2026, contains experimental results measuring signaling pathway activation, gene expression, and histological changes in gill tissue.

Use Cases

• Modeling the relationship between cadmium concentration and cellular injury markers based on the described exposure levels and histological observations.
• Analyzing gene expression patterns for detoxification and heat shock proteins based on the measured levels of CYP450, BAG3, PDI, Hsp21, Hsp27, and Hsp70.
• Investigating signaling pathway activation based on measurements of diacylglycerol, inositol-1,4,5-triphosphate, cytoplasmic calcium, and protein kinase C.
• Correlating biochemical markers with tissue damage based on described observations of filament swelling, dead epidermal cells, DNA degradation, and ATP decrease.

Strengths

• Data is derived from a controlled experiment with four specific cadmium exposure concentrations (0, 14.5, 29, and 58 mg/L).
• The study measures multiple biological endpoints, including gene expression, signaling molecules, and histological changes, providing a multi-faceted view of toxicity.
• Dataset is openly available under a CC-BY-4.0 license.

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The dataset is very small (35.5 KB), indicating a limited scope likely focused on summary results rather than raw observations.

Provenance

Source

figshare

Collection Method

Controlled laboratory exposure experiment.

Time Range

Experimental duration was 4 days.

Freshness

Last updated 2026-04-22 17:31:24; freshness should be verified.

Geography

Study organism is the freshwater crab Sinopotamon henanense; specific geographic collection location is not stated.