Exploratory Outcomes: Randomized Trial of Oxygenation Strategies in Acute Heart Failure

A multicenter, prospective, double-blinded randomized clinical trial comparing restrictive and liberal oxygenation strategies in patients hospitalized for acute heart failure. The dataset, shared by Ida Arentz Taraldsen on figshare, contains exploratory outcomes from the trial, which was last updated in May 2026. The primary outcome is pulmonary congestion measured by remote dielectric sensing after 24 hours.

Use Cases

• Compare the efficacy of restrictive versus liberal oxygen therapy based on the randomized treatment strategies described.
• Analyze changes in pulmonary congestion based on the primary outcome measured by remote dielectric sensing (ReDS).
• Investigate the relationship between peripheral oxygen saturation (SpO2) targets and patient outcomes in acute heart failure.
• Support meta-analyses on oxygenation guidelines for dyspnea and hypoxemia management.

Strengths

• Data originates from a prospective, double-blinded, randomized clinical trial, a robust study design.
• The trial is multicenter, which may improve the generalizability of findings.
• The dataset is shared under a permissive CC-BY-4.0 license, allowing for broad reuse.

Limitations

• The dataset is very small at 5.5 KB, indicating limited scope or a summary of results.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment for statistical modeling.

Provenance

Source

figshare, author Ida Arentz Taraldsen.

Collection Method

Investigator-initiated, multicenter, prospective, double-blinded, randomized clinical trial.

Time Range

The study timeframe is not specified in the provided metadata.

Freshness

Last updated 2026-05-22 17:41:55; freshness should be verified.

Geography

The geographic scope of the multicenter trial is not specified.