An expression matrix from the GEO database with accession GSE70528, used as a validation set in a study identifying hub genes linking osteoporosis and chronic kidney disease. The dataset is 6.6 MB in CSV format, authored by Hao Tang and last updated on 2026-05 04. It was used alongside GSE7158 to validate findings from training sets GSE15072 and GSE56815.
Use Cases
- Validating hub gene candidates for osteoporosis and chronic kidney disease based on the study's description.
- Conducting differential expression analysis similar to the methods described using the 'limma' package.
- Performing immune infiltration analysis to explore relationships with immune cells, as referenced in the study.
- Evaluating diagnostic performance of genes like FAM184A, NFKBIA, RP2, and HIRA using ROC curve analysis.
Strengths
- Dataset is 6.6 MB, indicating a manageable file size for analysis.
- Published under a CC-BY-4.0 license, permitting reuse with attribution.
- Serves as a validation set in a peer-reviewed bioinformatics study, suggesting curated relevance.
Limitations
- Row count and column definitions are unknown, limiting suitability assessment.
- Column-level documentation is absent; field semantics must be inferred after download.
- Description metadata is limited; actual data quality requires manual inspection after download.
Provenance
- Source
- figshare, originating from the GEO database (GSE70528).
- Collection Method
- Downloaded from the GEO database as a validation set for a bioinformatics study.
- Time Range
- null
- Freshness
- Last updated 2026-05-04 17:35:37; freshness should be verified.
- Geography
- null