Sex-Specific Determinants of IL-17A in a Zambian Adult Cohort

David Chisompola's dataset contains results from a cross-sectional study of 225 adults (71 males, 154 females) from Livingstone University Teaching Hospital in Zambia. It presents sex-stratified multiple linear regression models identifying sociodemographic, clinical, and inflammatory correlates of circulating Interleukin-17A (IL-17A) levels. The data was last updated on 2026-05-18.

Use Cases

• Investigating sex-specific biomarker associations based on the described regression results for IL-17A.
• Analyzing relationships between inflammatory cytokines (e.g., IL-6, IL-1β, IFN-γ) and IL-17A in male participants.
• Studying non-cytokine determinants of immune markers based on the identified association between plasma potassium and IL-17A in females.
• Examining HIV status as a potential covariate in cytokine networks based on the reported non-significant finding in males.

Strengths

• Dataset is focused on a specific, understudied research question regarding sex-specific determinants of IL-17A.
• Includes data from 225 participants with sex-stratified analysis (71 males, 154 females).
• Analysis incorporates multiple data types mentioned in the description: sociodemographic, clinical, metabolic, and a panel of inflammatory cytokines.

Limitations

• Row count and column-level documentation are unknown, which limits suitability assessment.
• The dataset is very small at 5.5 KB, indicating limited scope, likely containing only summary regression results.
• Data is from a single-site study in Zambia, which may limit generalizability.

Provenance

Source

David Chisompola, via figshare.

Collection Method

Cross-sectional study with plasma cytokine measurements and clinical data collection from a hospital cohort.

Freshness

Last updated 2026-05-18 17:40:42; freshness should be verified.

Geography

Zambia (Livingstone University Teaching Hospital).