Gene Ontology Enrichment Results for H3K18La Peaks in Retina Development

Functional gene enrichment analysis results link histone modification H3K18La peaks in promoter regions to RNA-seq expression during retina development. The 25.1 KB Excel file, authored by Mohita Gaur and updated in April 2026, contains statistical outputs from Gene Ontology Biological Process analysis.

Use Cases

• Identify biological pathways enriched for genes with H3K18La promoter peaks using the 'p.adjust' column for statistical significance.
• Assess the proportion of pathway-specific genes via the 'GeneRatio' and 'BgRatio' columns.
• Filter enrichment results for peaks positively or negatively correlated with RNA-seq expression from the retina.
• Validate epigenetic markers by correlating H3K18La peak quantitation data with gene expression changes.

Strengths

• Includes key statistical metrics like the Benjamini-Hochberg false discovery rate in the 'p.adjust' column.
• Data is focused on a specific biological context: retina development and H3K18La histone modification.
• Released under a permissive CC-BY-4.0 license for reuse.

Limitations

• Very small dataset at 25.1 KB, indicating limited scope with likely fewer than 100 rows of enrichment results.
• Unknown row count and specific column list beyond the few described.
• Temporal coverage for the underlying experimental data is not specified.

Provenance

Source

Figshare repository, authored by Mohita Gaur.

Collection Method

Derived from functional gene enrichment analysis of Gene Ontology Biological Process terms applied to quantitated H3K18La peaks and RNA-seq expression data.

Time Range

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Freshness

Last updated in April 2026, indicating planned future maintenance.

Geography

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