Fig 6 String MCL Clusters: Hippocampus RNA Sequencing in High- and Low-Excitability Rats

Marina Pavlova published bulk RNA sequencing data from the hippocampus of selectively bred rat strains on figshare in June 2026. The dataset compares transcriptomic profiles of high-excitability (LT) and low-excitability (HT) rats, highlighting differences in synaptic, glial, and cellular maintenance pathways. The data is stored in an XLS file sized 42.5 KB.

Use Cases

• Identify strain-specific transcriptional profiles based on differential expression analysis mentioned in the description.
• Analyze differences in synaptic organization and neuronal projection development based on functional annotation.
• Investigate glial/immune functions and neurovascular regulation pathways highlighted in the description.
• Cross-model comparisons of excitability-related traits using the reference transcriptomic profile.
• Generate hypotheses for follow-up structural and functional tissue-level measurements based on the analysis.

Strengths

• Data is derived from a long-term selective-breeding paradigm, providing a model for inherited differences.
• The dataset is openly available under a CC-BY-4.0 license.
• Analysis covers multiple biological domains including synapse-related genes, glial functions, and extracellular matrix remodeling.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small (42.5 KB), indicating limited scope.

Provenance

Source

figshare

Collection Method

Bulk RNA sequencing of hippocampus tissue from selectively bred rat strains.

Freshness

Last updated 2026-06-03 17:37:38; freshness should be verified.