HIV-1 Infectivity and p24 Secretion Correlation Data

15.9 MB Excel dataset contains experimental results from a high-content imaging reporter assay using modified GHOST cells. The assay enables rapid evaluation of HIV-1 infectivity and direct correlation with p24 secretion for deeper interrogation of viral kinetics. Data was authored by Teresa LuPone and last updated in March 2026.

Use Cases

• Analyze the correlation between HIV-1 infectivity measurements and p24 secretion levels from collected supernatants.
• Model HIV-1 replication dynamics using infectivity data from the GHOST cell fluorescence reporter assay.
• Benchmark viral infectivity and tropism across different samples within the experimental pipeline.

Strengths

• Dataset is 15.9 MB in size, stored in an accessible XLSX format.
• Assay is designed for consistency and replicability when evaluating large numbers of samples.
• Published under a permissive CC BY 4.0 license for reuse.

Limitations

• Specific row count, column names, and sample data are unavailable, limiting preliminary assessment of structure.
• Data scale is relatively small at 15.9 MB, which may constrain the complexity of analytical models.
• Dataset focuses on a specific in vitro assay using GHOST cells, which may limit generalizability to in vivo contexts.

Provenance

Source

figshare, authored by Teresa LuPone.

Collection Method

High-content imaging reporter assay using modified human osteosarcoma GHOST cells that fluoresce in response to HIV-1 infection.

Time Range

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Freshness

Last updated March 2026.

Geography

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