HIV-1 Infectivity and p24 Secretion Correlation Data

12.3 KB Excel file contains experimental data from a high-content imaging reporter assay using modified GHOST cells. The assay enables rapid evaluation of HIV-1 infectivity and direct correlation with p24 secretion in supernatants. Author Teresa LuPone published the data on figshare in March 2026 under a CC BY 4.0 license.

Use Cases

• Correlate HIV-1 infectivity fluorescence readings with p24 secretion levels to model viral replication kinetics.
• Analyze infectivity data from GHOST cells to assess the impact of Antiretroviral Therapy (ART) on viral particle functionality.
• Use experimental pipeline data to benchmark HIV-1 tropism and pathogenicity in distinct cell populations.

Strengths

• Data supports direct correlation between two key virology metrics: infectivity and p24 secretion.
• Assay method is described as enabling rapid evaluation with consistency and replicability for large sample numbers.
• Published under a permissive CC BY 4.0 license, facilitating reuse and analysis.

Limitations

• Dataset is very small at 12.3 KB, indicating limited scope and likely a small number of experimental observations.
• Specific row count, column structure, and sample data are unavailable, hindering immediate assessment of analytical utility.
• Data originates from a single figure in a study, representing a specific experimental snapshot rather than a longitudinal collection.

Provenance

Source

figshare, authored by Teresa LuPone.

Collection Method

High-content imaging reporter assay using modified human osteosarcoma (GHOST) cells fluorescing in response to HIV-1 infection.

Time Range

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Freshness

Last updated March 2026.

Geography

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