Multimodal Intervention Trial Data for Children with Autism

Kazi Md Azman Hossain published a study protocol for a randomized controlled trial evaluating a five-component multimodal intervention on executive function in children with Autism Spectrum Disorder. The trial plans to enroll 130 children with ASD and 65 typically developing children as controls, with data collection spanning baseline, 12-week, and 24-week follow-up assessments. The protocol was registered in November 2025 and the dataset was last updated in March 2026.

Use Cases

• Analyze changes in inhibitory control scores from the Go/No-Go Task between the experimental and wait-list control groups.
• Model the relationship between intervention sessions and improvements in cognitive flexibility measured by the Trail Making Test A-B.
• Compare working memory performance, assessed via the Corsi Block Tapping Task and Digit Span tests, across children with ASD and typically developing controls.
• Evaluate correlations between primary executive function outcomes and secondary behavioral scores from the Social Responsiveness Scale-2.
• Assess the longitudinal effect of the 12-week intervention by tracking Autism Treatment Evaluation Checklist scores at three time points.

Strengths

• Dataset originates from a prospectively registered, assessor-blinded, double-center randomized controlled trial.
• Outcomes are measured across three executive function domains and two secondary behavioral scales.
• Includes a control group of 65 typically developing children for comparative analysis.

Limitations

• The dataset is very small at 9.5 KB, indicating limited scope and likely summary-level data rather than individual participant records.
• Geographic coverage is limited to two centers in Bangladesh, which may affect generalizability.
• Specific sample sizes for each assessment metric and raw data availability are unknown.

Provenance

Source

figshare, author Kazi Md Azman Hossain.

Collection Method

Data will be collected via standardized clinical assessments (e.g., Go/No-Go Task, Trail Making Test) as part of a randomized controlled trial.

Time Range

Data collection covers baseline, 12-week, and 24-week follow-up periods.

Freshness

Protocol registered in November 2025; dataset last updated March 2026.

Geography

Bangladesh (two trial centers).