HIV Cardiovascular Risk Biomarker Panel for Inflammatory Profile Clustering

A 24-marker initial panel of biomarkers linked to cardiovascular phenotype in people with HIV, expanded with 31 exploratory biomarkers. The dataset was created by Rachel Mac Cann and published on figshare under a CC-BY-4.0 license, last updated on 2026-04 27. It is a 9.5 KB Excel file used to evaluate recursive feature addition models for biomarker-driven clustering.

Use Cases

• Develop unsupervised clustering models based on inflammatory biomarker profiles.
• Identify biomarker combinations predictive of cardiovascular risk in people with HIV.
• Compare recursive feature addition (RFA) model frameworks for feature selection.
• Analyze associations between immune activation biomarkers and clinical outcomes.

Strengths

• Includes a 24-marker initial panel and 31 exploratory biomarkers for analysis.
• Specific results are reported, such as an adjusted odds ratio of 2.3 for a key cluster.
• Dataset is openly licensed under CC-BY-4.0, facilitating reuse.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The 9.5 KB file size suggests a very limited scope of data.

Provenance

Source

figshare

Collection Method

Biomarker data likely collected from clinical studies of people with and without HIV.

Time Range

null

Freshness

Last updated 2026-04-27 17:33:22; freshness should be verified.

Geography

null