Drosophila Immune Response Data Against Fungal Pathogens

Statistical models and outputs from a study of Drosophila melanogaster immune defense mechanisms against diverse fungal pathogens. The dataset includes analysis of the Toll pathway, melanization, and fungal protease detection roles. It is provided in an XLSX file of 204.5 KB.

Use Cases

• Analyze the role of the Toll pathway in limiting fungal proliferation across diverse fungal pathogens.
• Compare the effectiveness of melanization versus phagocytosis or the Imd pathway in limiting fungal entry.
• Investigate the quantitative role of fungal protease detection by Persephone versus the glucan sensor GNBP3 in Toll pathway activation.
• Examine the immune evasion strategy of the obligate fungus Entomophthora muscae using its vegetative development data.

Strengths

• Data originates from a peer-reviewed scientific study dissecting immune defense mechanisms.
• Includes analysis of multiple immune components like the Toll pathway, melanization, and specific sensors.
• Published under the permissive CC BY 4.0 license for wide reuse.

Limitations

• The dataset is small in scale at 204.5 KB, indicating limited raw data or summary statistics.
• Specific row counts, column structures, and sample data are unavailable, limiting immediate analytical utility.
• Focus is on a specific model organism (Drosophila) and fungal pathogens, limiting generalizability.

Provenance

Source

figshare, authored by Guiqing Liu.

Collection Method

Experimental data and statistical outputs from a study using Drosophila melanogaster as a model organism.

Freshness

Last updated on 2026-03-23.