gBlocks DNA fragments used for constructing CRISPR/Cas9 knockout plasmids targeting the Histoplasma fungal pathogen. The dataset, shared by author Nebat Ali on figshare, is 9.3 KB in size and was last updated in March 2026. It supports research into the role of histone deacetylase Rpd3 in regulating thermal dimorphism and virulence.
Use Cases
- Constructing CRISPR/Cas9 knockout plasmids based on the described gBlocks fragments.
- Studying the role of histone deacetylase Rpd3 in thermal dimorphism based on the research context.
- Analyzing gene expression regulation of morphology-specific genes and virulence factors mentioned in the description.
- Investigating chromatin regulation's impact on temperature response in a fungal pathogen.
Strengths
- Dataset is openly licensed under CC-BY-4.0.
- File size is precisely 9.3 KB, indicating a compact, focused dataset.
- Last update date is explicitly provided as 2026-03-17.
Limitations
- Row count and column definitions are unknown, limiting suitability assessment.
- Column-level documentation is absent; field semantics must be inferred after download.
- The dataset's 9.3 KB size indicates a very limited scope.
Provenance
- Source
- figshare, author Nebat Ali.
- Collection Method
- Likely generated as part of research on Histoplasma thermal dimorphism and chromatin regulation.
- Time Range
- Publication date suggests data is contemporary to the described research.
- Freshness
- Last updated 2026-03-17 17:33:27.
- Geography
- null