Gene Lists of Gene Sets A-D: Transcriptomic Profiles from MAP-Infected Ileal Organoids

Gene lists derived from a time-course transcriptomic profiling study of patient-derived ileal organoids. The data was generated by Paula E. Schweizer and published on figshare in June 2026. The study compared organoids microinjected with Mycobacterium avium subsp. paratuberculosis (MAP) or treated with forskolin against untreated controls over 48 hours.

Use Cases

• Identify culture-induced transcriptional drift based on time-course gene expression changes.
• Analyze pathogen-specific gene set responses based on MAP infection data.
• Investigate the confounding effects of pharmacological interventions based on forskolin treatment data.
• Study spatial gene expression patterns in enterocytes based on crypt-villus junction downregulation findings.

Strengths

• Data is derived from patient-derived ileal organoids, a relevant human tissue model.
• Includes a 48-hour time-course analysis of transcriptomic changes.
• Uses spatial transcriptomics to validate culture-induced effects.

Limitations

• The dataset is very small at 12.5 KB, indicating limited scope.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

figshare

Collection Method

Time-course transcriptomic profiling of microinjected and treated patient-derived ileal organoids.

Time Range

Experimental time course of 48 hours.

Freshness

Last updated 2026-06-04 18:00:13; freshness should be verified.