Gene Set Enrichment Analysis for Top Principal Components

A list of genes with the highest positive and negative contributions to the top five principal components from a larger analysis. The 5.5 KB Excel file was created by Costas Bampos and last updated on April 15, 2026. It contains results from a Reactome pathway gene set enrichment analysis.

Use Cases

• Identify biological pathways associated with major sources of variation based on principal component loadings.
• Validate or interpret principal component analysis results from gene expression studies.
• Prioritize genes for further functional study based on their contribution to principal components.

Strengths

• Data is shared under a permissive CC-BY-4.0 license.
• File size is 5.5 KB, indicating a focused and easily downloadable dataset.

Limitations

• Row count and specific column definitions are unknown, limiting suitability assessment.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

Costas Bampos via figshare

Collection Method

Derived from principal component analysis and subsequent Reactome pathway enrichment analysis.

Freshness

Last updated 2026-04-15 17:47:16; freshness should be verified.