10.9 KB of genomic coordinates for merged cis-regulatory element (CRE) peaks for the LDLR gene. The data was created by Kyle Leix and last updated on March 17, 2026. The peaks were derived from merged rolling 100 bp windows and are associated with a significant reduction in LDL uptake upon disruption.
Use Cases
- Identifying potential noncoding regulatory regions for the LDLR gene based on the described CRE peaks.
- Prioritizing candidate genetic variants from genome-wide association studies (GWAS) based on overlap with these functional genomic coordinates.
- Training models to predict regulatory element activity based on genomic features mentioned in the description.
- Designing CRISPR-based functional assays to test the impact of disrupting specific genomic intervals.
Strengths
- Data is openly licensed under CC-BY-4.0.
- The dataset is small (10.9 KB), ensuring fast download and processing.
Limitations
- Row count is unknown, which may limit suitability assessment.
- Column-level documentation is absent; field semantics must be inferred after download.
- Description metadata is limited; actual data quality requires manual inspection after download.
Provenance
- Source
- figshare, author Kyle Leix.
- Collection Method
- Merged CRE peaks derived from rolling 100 bp windows demonstrating a significant reduction in LDL uptake upon disruption.
- Time Range
- null
- Freshness
- Last updated 2026-03-17 17:32:03; freshness should be verified.
- Geography
- null