GSEA Enrichment: Genetic Loci for Age-Related Eye Disease

A genomic dataset identifies genetic factors for Age-related eye disease (ARED). It contains results from Genomic Structural Equation Modeling and transcriptome-wide association analyses, identifying 11 genome-wide significant loci. The dataset was authored by Luqi Gao and last updated on 2026-05-14.

Use Cases

• Prioritizing candidate SNPs for functional validation based on the 11 identified genome-wide significant loci.
• Conducting tissue- and cell layer-specific gene signal analysis based on transcriptome-wide association approaches.
• Performing functional annotation of genetic variants in relation to ARED based on the described enrichment analysis.

Strengths

• Identifies 11 genome-wide significant loci associated with ARED.
• Applies multiple analysis methods including Genomic-SEM and diverse transcriptome-wide association approaches.
• Released under a permissive CC-BY-4.0 license.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small at 9.5 KB, indicating limited scope.

Provenance

Source

figshare, author Luqi Gao.

Collection Method

Genomic Structural Equation Modeling (Genomic-SEM) and Post-processing analysis of Genome-Wide Association Studies (GWAS).

Freshness

Last updated 2026-05-14 17:48:56; freshness should be verified.