High-Confidence FDA-Approved Drug-Gene Interactions from DGIdb

A 5.5 KB Excel file lists high-confidence drug-gene interactions with an interaction score of at least 2.0, sourced from the DGIdb database. The dataset was authored by Nosayba Al-Damook and last updated on June 4, 2026. It is shared under a CC-BY-4.0 license on figshare.

Use Cases

• Prioritizing drug candidates for repurposing based on high-confidence gene targets.
• Validating computational predictions of drug-target interactions against a curated benchmark.
• Analyzing the landscape of FDA-approved drugs and their associated gene targets.

Strengths

• Interaction confidence is explicitly filtered (score ≥2.0), providing a quality threshold.
• Dataset is small (5.5 KB), facilitating quick inspection and integration.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality requires manual inspection after download.

Provenance

Source

DGIdb (Drug-Gene Interaction Database)

Collection Method

Identified via DGIdb, filtered for high-confidence interactions (score ≥2.0).

Freshness

Last updated 2026-06-04 17:27:42; freshness should be verified.