Upregulated miRNAs in Sensorineural Hearing Loss Mouse Model

Three specific miRNAs—miR-224-5p, miR-339-5p, and miR-1198-5p—were identified as regulators of Neuritin expression in a mouse model of sensorineural hearing loss. Pingping Meng published this 5.5 KB Excel dataset on figshare in May 2026. The data likely contains results from high-throughput sequencing and bioinformatics analysis of cochlear tissues.

Use Cases

• Validate miRNA inhibitors as therapeutic targets based on the identified miR-224-5p, miR-339-5p, and miR-1198-5p.
• Study the molecular mechanism of Neuritin expression regulation based on miRNA screening results.
• Analyze miRNA expression patterns in cochlear tissues based on high-throughput sequencing data.
• Develop bioinformatics models for miRNA-target interactions based on the regulatory effects described.

Strengths

• Dataset is licensed under CC-BY-4.0, allowing for open reuse.
• The description provides a clear biological context and specific miRNA names.
• File size is 5.5 KB, indicating a focused and manageable dataset.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data is from a single mouse model study, which may limit generalizability.

Provenance

Source

figshare

Collection Method

High-throughput sequencing and bioinformatics analysis of cochlear tissues from a mouse model of sensorineural hearing loss.

Freshness

Last updated 2026-05-21 17:30:54; freshness should be verified.