Hub Genes Prioritized from a PPI Network of ~6,500 DEGs

~6,500 differentially expressed genes (DEGs) were analyzed to identify hub genes prioritized by overlap across four cytoHubba topological methods. Gene locations and aliases are provided for annotation. The dataset was authored by Negar Mottaghi-Dastjerdi and last updated on May 21, 2026.

Use Cases

• Prioritizing key regulatory genes based on topological analysis of a PPI network.
• Annotating gene lists with chromosomal locations and alternative names.
• Comparing gene centrality across different network analysis methods.
• Identifying potential therapeutic targets from a large set of differentially expressed genes.

Strengths

• Focuses on hub genes from a network of ~6,500 DEGs, providing a filtered, high-priority subset.
• Prioritization is based on consensus across four distinct cytoHubba topological methods.
• Includes annotation data such as gene locations and aliases.

Limitations

• Description metadata is limited; actual data quality requires manual inspection after download.
• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.

Provenance

Source

figshare

Collection Method

Hub genes derived from a protein-protein interaction (PPI) network analysis of differentially expressed genes (DEGs).

Freshness

Last updated 2026-05-21 17:30:19; freshness should be verified.