ELAVL4 and PABPC4L Gene Expression During Lytic Reactivation

5.5 KB of normalized Bru-seq read counts for nascent ELAVL4 and PABPC4L transcripts. The data, authored by Derek Daigle and published in 2020, captures two replicates from HH514-16 cells exposed to sodium butyrate for 3, 24, and 48 hours to study lytic cycle reactivation.

Use Cases

• Analyze transcriptional upregulation of ELAVL4 and PABPC4L based on time-series data from lytic reactivation.
• Compare gene expression profiles between replicates to assess experimental reproducibility.
• Model the kinetics of viral lytic cycle reactivation based on host gene expression changes.

Strengths

• Includes data from two biological replicates, which suggests reproducibility checks are possible.
• Provides normalized read counts, a standard metric for comparative gene expression analysis.
• Time-series data captures three distinct time points (3, 24, and 48 hours) during the reactivation process.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The dataset is very small (5.5 KB), indicating a limited scope focused on two specific genes.

Provenance

Source

figshare

Collection Method

Bru-seq datasets derived from HH514-16 cells exposed to NaB.

Freshness

Last updated 2026-05-11 17:46:08; freshness should be verified.