AMP V703 and V704: IC50 and IC80 Scores for Study Sequences

IC50 and IC80 scores for antimicrobial peptide (AMP) study sequences V703 and V704. The dataset, created by Bette Korber and shared under a CC-BY-4.0 license, groups transmitted founder lineages from individuals and marks the most and least sensitive variants for panel design. It is a small 52.0 KB Excel file last updated in April 2026.

Use Cases

• Comparing peptide sensitivity across different study sequences (V703 vs V704) based on the reported IC50 and IC80 scores.
• Identifying the most and least sensitive variants from an individual for panel design, as indicated by the grey and yellow markings.
• Analyzing the impact of transmitted founder lineage grouping on sensitivity measurements, as described in the grouping methodology.

Strengths

• Provides two standard pharmacological potency metrics (IC50 and IC80) for comparison.
• Explicitly marks the most and least sensitive variants per individual for specific panel design purposes (SHEP-T2 and REP-T2).
• Shared under a permissive CC-BY-4.0 license, facilitating reuse.

Limitations

• Row count is unknown, which may limit suitability assessment for large-scale analysis.
• Column-level documentation is absent; field semantics must be inferred after download.
• Description metadata is limited; actual data quality and completeness of 'ND' (not done) entries require manual inspection.

Provenance

Source

figshare

Collection Method

Likely derived from experimental assays on antimicrobial peptide sequences.

Time Range

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Freshness

Last updated 2026-04 23 17:40:33; freshness should be verified.

Geography

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