CMV-Specific T-Cell Counts from ELISPOT and ICS Assays in 30 Healthy Adults

Data from 30 healthy adult participants, with a mean age of 37.8 years, collected to compare two assays for quantifying human cytomegalovirus (HCMV)-specific T-cells. The dataset includes counts of IFN-γ-producing cells from ELISPOT and intracellular cytokine staining (ICS) assays, stimulated with whole CMV lysate and IE1 peptide pool, alongside anti-CMV IgG serology results. It was authored by Chompunuch Klinmalai and last updated on June 4, 2026.

Use Cases

• Correlating T-cell response measurements from ELISPOT and intracellular cytokine staining (ICS) assays based on the described comparative study.
• Analyzing the relationship between CMV-specific T-cell counts and anti-CMV IgG serological status as explored in the description.
• Benchmarking assay performance for quantifying IFN-γ-secreting cells in response to whole CMV lysate and IE1 peptide pool stimulation.

Strengths

• Includes data from 30 participant samples, enabling statistical correlation analysis.
• Correlation coefficients (e.g., r=0.7677 for whole CMV) between assay methods are explicitly provided in the source description.
• Dataset pairs immunological assay results (ELISPOT, ICS) with serological status (anti-CMV IgG) for each participant.

Limitations

• Row count and specific column definitions are unknown, requiring inspection after download.
• The dataset is very small at 9.5 KB, limiting the scope of analysis.

Provenance

Source

figshare, author Chompunuch Klinmalai.

Collection Method

Laboratory assay data from peripheral blood samples of healthy volunteers, analyzed using ELISPOT, ICS, and chemiluminescent immunoassay.

Freshness

Last updated 2026-06-04 17:24:31.