Immunofluorescence Images of GFAP in Intracerebral Hemorrhage Mouse Model

Figshare hosts a collection of immunofluorescence images of GFAP (glial fibrillary acidic protein) from a study on intracerebral hemorrhage in mice. The data, provided in an XLSX file of 10.5 KB, was generated by author Tingting Chen to assess the effects of GABAAR modulators on synaptic plasticity and neural repair. The dataset includes tags for synaptic plasticity, neuroscience, and immunofluorescence.

Use Cases

• Analyze GFAP expression patterns in immunofluorescence images to correlate with treatment groups (CL218872 vs. MRK-016) from the described mouse model.
• Quantify changes in synaptic plasticity-related molecules like BDNF, GAP-43, PSD-95, and synaptophysin referenced in the study results.
• Correlate image-based GFAP data with histological outcomes such as neuronal density and synaptic connectivity mentioned in the research methods.
• Use the immunofluorescence image data to validate findings on inflammation markers like phospho-p65, IL-6, and TNF-α described in the study results.

Strengths

• Dataset is openly licensed under CC BY 4.0, facilitating reuse and sharing.
• Focuses on a specific, well-defined neuroscience research context: GFAP in an intracerebral hemorrhage mouse model.
• Associated with a detailed methodological description including treatments (CL218872, MRK-016) and outcome measures (inflammation, synaptic molecules).

Limitations

• Very small data volume at 10.5 KB, indicating a limited number of images or data points.
• Unknown row and column structure, as the specific data format within the XLSX file is not detailed.
• Data scope is restricted to a single, specific experimental model (collagenase IV-induced ICH in mice), limiting generalizability.

Provenance

Source

Figshare, authored by Tingting Chen.

Collection Method

Generated from an experimental intracerebral hemorrhage mouse model constructed using collagenase IV, with treatments of GABAAR modulators CL218872 or MRK-016.

Freshness

Last updated on 2026-03-23.