Immunological Parameters of Enrolled Subjects: CMV-Specific T-Cell and Antibody Data

Thirty peripheral blood samples from healthy individuals quantify CMV-specific T-cells and anti-CMV IgG levels. The dataset compares results from intracellular staining (ICS) and enzyme-linked immunospot (ELISPOT) assays, showing a strong correlation between the two methods. It was authored by Chompunuch Klinmalai and last updated on June 4, 2026.

Use Cases

• Correlating CMV-specific T-cell counts from ICS and ELISPOT assays based on whole CMV and IE1 antigen stimulation.
• Analyzing the relationship between CMV-specific T-cell immunity and anti-CMV IgG serological status.
• Benchmarking immunological assay performance for monitoring CMV reactivation risk in immunocompromised patients.

Strengths

• Includes data from 30 healthy participants with a mean age of 37.8 years.
• Reports strong statistical correlations (e.g., r=0.7677) between two major immunological assay types.
• Contains concomitant anti-CMV IgG level analysis for 28 seropositive and 2 seronegative individuals.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• Data may reflect demographic bias inherent to the specific cohort of 30 healthy volunteers.

Provenance

Source

figshare

Collection Method

Laboratory analysis of peripheral blood samples using ICS, ELISPOT, and chemiluminescent immunoassays.

Freshness

Last updated 2026-06-04 17:24:30; freshness should be verified.