Dapivirine Vaginal Ring Adherence Meta-Analysis for HIV Prevention

A meta-analysis of 15 articles published between 2016 and 2024, summarizing evidence on adherence to the Dapivirine Vaginal Ring for HIV-1 prevention among African women aged 16–45. The dataset includes data from seven unique studies, reporting on 2,424 women using the ring, with adherence outcomes measured as proportions, means, and visit/ring adherence. It was created by Roseline Dzekem Dine and last updated in May 2026.

Use Cases

• Estimate pooled adherence rates for the Dapivirine Vaginal Ring based on the reported meta-analysis of proportions and means.
• Analyze factors influencing adherence across multiple domains as described in the included studies.
• Assess the certainty of evidence for DVR adherence using the GRADE approach framework mentioned in the description.

Strengths

• Includes data from 15 articles across seven unique studies, providing a multi-study perspective.
• Reports on 2,424 women using the Dapivirine Vaginal Ring from four of the included studies.
• Adherence metrics are calculated with confidence intervals, such as a pooled mean estimate of 84% (95% CI: 75%–91%).

Limitations

• Column-level documentation is absent; field semantics must be inferred after download.
• Row count is unknown, which may limit suitability assessment.
• The certainty of the evidence for adherence was assessed as very low according to the description.

Provenance

Source

Roseline Dzekem Dine

Collection Method

Systematic review and meta-analysis of observational studies and randomized trials retrieved from multiple databases.

Time Range

Studies published between 2016 and 2024.

Freshness

Last updated 2026-05-18 17:34:41; freshness should be verified.

Geography

Focus on African women aged 16–45 years.