Phagocytosis Model Data with Membrane Tension Parameters

A 5.5 KB Excel file containing initial and boundary conditions for a mathematical model of phagocytosis. The model, created by Peyman Shadmani, explicitly incorporates membrane tension and a coupled signaling component to simulate receptor motion and engulfment dynamics. It was last updated in April 2026.

Use Cases

• Simulate receptor motion dynamics using the provided initial and boundary conditions.
• Analyze the impact of membrane tension parameters on predicted engulfment speed and stall events.
• Study the coupling between signaling component variables and receptor dynamics via the tension parameter.
• Validate model predictions against experimental observations of frustrated phagocytosis.

Strengths

• Explicitly models membrane tension, a key physical parameter often overlooked in phagocytosis models.
• Includes a signaling component coupled to receptor dynamics, enabling analysis of regulatory interactions.
• Released under a permissive CC-BY-4.0 license for open reuse and modification.

Limitations

• Very small dataset at 5.5 KB, indicating limited scope and likely few rows or parameters.
• Data format is proprietary XLS, requiring specific software for access.
• Model parameters and results are not empirically validated within the dataset itself.

Provenance

Source

Figshare, authored by Peyman Shadmani.

Collection Method

Parameters and conditions derived for a theoretical mathematical model.

Time Range

Model conditions are not temporally bound.

Freshness

Last updated in April 2026.

Geography

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