ISG Overlap with CBL-Regulated Genes in Mtb-Infected Macrophages

A 13.7 KB text file published by Tina Truong on figshare in March 2026. The dataset relates to a study of the ubiquitin ligase CBL in Mycobacterium tuberculosis-infected macrophages, identifying over 46,000 ubiquitylated peptides and roughly 400 with CBL-dependent ubiquitylation.

Use Cases

• Analyzing CBL-dependent ubiquitylation events based on the identification of roughly 400 peptides.
• Studying antiviral versus antibacterial immune response regulation based on the described gene expression suppression.
• Investigating potential CBL substrates like Fas-associated factor 2 (FAF2) based on the genetic interaction analysis mentioned.

Strengths

• Identifies over 46,000 ubiquitylated peptides in Mtb-infected macrophages.
• Highlights roughly 400 peptides with CBL-dependent ubiquitylation.
• Released under a permissive CC-BY-4.0 license.

Limitations

• Row count is unknown, which may limit suitability assessment.
• Column-level documentation is absent; field semantics must be inferred after download.
• The 13.7 KB size indicates a very limited data scope.

Provenance

Source

figshare, author Tina Truong.

Collection Method

Data likely generated from mass spectrometry and genetic interaction analysis as described.

Time Range

null

Freshness

Last updated 2026-03 17:36:43.

Geography

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